Take a deeper look at Vasotop...

Vasotop

ACEi's

Local ACE

Effects on the heart

Effects on blood vessel walls

Effects on the kidney

Summary

Datasheet

References

 

All ACEi's seem the same...

Inhibition of systemic ACE leads to vasodilation and a reduction in blood pressure. All ACEi's work at this level.

However, Vasotop is also active on a local level...

"Possibly due to its high lipophilicity and strong diffinity to the converting enzyme, a better tissue penetration and a more pronounced local ACE inhibition in the target organs has been observed, as compared to other ACE inhibitors."

Various tissues become involved early on in heart failure and undergo degenerative changes. That's why it is now strongly argued that inhibiting ACE on a local level is of more significance.